Step 1: DNA+Protein Pipeline

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The single-cell MRD pipeline consists of two steps: (1) the standard DNA+Protein pipeline, followed by (2) the MRD pipeline for detection of rare somatic variants. The processing steps for the DNA+Protein pipeline can be found here. The H5 file created by the DNA+Protein pipeline is used by the MRD pipeline to generate the somatic mutations, clonal architecture, and protein expression profile report.


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