- Translocation Detection - Addition of Translocation assay in addition to other genome editing events that allows for the precise measurement of translocations, or chromosomal rearrangements.
- Seamless Integration of Antibody based demultiplexing - Tapestri can now be used to multiplex genome editing data based on the differences in the protein expressions across samples. This allows processing of multiple patient samples on a single Tapestri run as opposed to multiple Tapestri runs, one for each patient. The Tapestri Pipeline application can then be used to classify each cell into its original sample category. GE DNA with automatic antibody based demultiplexing analysis is supported by GE DNA+Protein pipeline.
- Improved read trimming by use of cutadapt v4 - Cutadapt V4 has a hybrid algorithm for adapter alignment that results in a more intuitive and better trimming. This resulted in the following changes for the Tapestri data -
- Better read recovery for Protein.
- Non-informative reads from DNA are discarded at the first step. In case any DNA data is reprocessed a difference in cell counts is expected as this change results in an update to the alignment step which in turn impacts the cell finder output.
27 March 2024 Tapestri GE DNA, GE DNA + Protein Pipeline v1.1.1
- Updated
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