Tapestri DNA Pipeline v1.6 2018

  • Updated

Key features

  • Streamlined data analysis from FASTQ files to annotated VCF files
  • Targeted and accurate SNVs and indel variant calling
  • Create multiple data output files that seamlessly plug into Tapestri Insights and other third-party software packages

Main input/output files

Input files

  • FASTQ files in compressed format (fastq.gz) generated from Illumina MiSeq, HiSeq 2500, HiSeq 4000, or NovaSeq 6000 runs
  • Panel .zip file from Tapestri Designer in a compressed format that provides a user-defined set of targeted positions, such as the Acute Myeloid Leukemia (AML) panel

Primary output files

  • LOOM file – Used in Tapestri Insights
  • VCF in compressed format (vcf.gz) – Used with third-party software platforms
  • Report file in PDF format – Summarizes sequencing metrics and outputs the total cell number
  • Barcode read distribution file – Used for SNV, CNV, and protein analysis
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