The allele dropout (ADO) occurs when a sample is genotyped and one or both alleles are not present. Tapestri’s ADO rate is < 10 %.
The doublet rate is the fraction of multiple cells encapsulated within a single oil droplet that can impact data analysis and interpretation if not adequately addressed. Tapestri’s doublet rate is < 8 %.
The limit of detection (LOD) is the lowest quantity or concentration of a component that can be reliably detected with a given analytical method.
For the Measurable Residual Disease (MRD) assay, the LOD for SNVs is a 0.01% subclonal population, assuming a pre-enrichment process.
*The limit of detection for indels and ITDs depends on the length and nature of the variant.