Sample format

• Cryopreserved samples, such as 10 % DMSO + media/FBS
• Cultured cells
• Fresh tissue biopsies – Use Nuclei Extraction protocol or publicly available enzymatically dissociation, DNase-free protocols
• OCT-embedded tissues – Use Nuclei Extraction protocol
• Alcohol-based fixed cells, such as acetic acid, EtOH, and MeOH
• Average cell size must be < 35 µm

Tissue types

• Cell lines, such as K562 and RAJI
• PBMCs
• Bone-marrow-derived cells
• Breast tumor
• Lung tumor
• Colorectal tumor
• Prostate tumor
• Astrocytoma
• Glioblastoma multiforme 
• Pancreatic tumor
• Chest wall soft tissue metastatic tissue melanoma
• Lung metastatic tissue melanoma
• Liver metastatic tissue melanoma
• Liver
• Patient-derived xenograft (PDX) samples, such as mouse
• Mouse-derived cells
• Viral-infected cells

Not yet validated

• Formalin-fixed paraffin-embedded (FFPE) samples
• Paraformaldehyde (PFA) fixed cells
• Frozen cell pellets
• Circulating tumor cells (CTCs)
• Sperm cells

Not supported

• Cell-free DNA (cfDNA)
• Prokaryotes